Publications

Guzmán-Vélez E, Rivera-Hernández A, Fabrega S, Oliveira G, Martínez JE, Baena A, Picard G, Lopera F, Arnold SE, Taylor JA, Quiroz YT. Relationship between physical activity and biomarkers of pathology and neuroinflammation in preclinical autosomal-dominant Alzheimer’s disease. Alzheimers Dement (N Y). 2024 Nov 28;10(4):e70003. doi: 10.1002/trc2.70003. PMID: 39748841; PMCID: PMC11694529.


McDowell C, Giudicessi A, Martinez JE, Badillo-Cabrera AL, Bonillas Félix NA, Martinez L, Munera D, Vila-Castelar C, Schwab N, Ramirez-Gomez L, Saldana DG, Gonzalez Catalan M, Amariglio R, Duffy JF, Cronin-Golomb A, Quiroz YT. Sleep apnea risk, subjective cognitive decline, and cognitive performance: Findings from the Boston Latino Aging Study (BLAST). Dement Geriatr Cogn Disord. 2024 Nov 25:1-14. doi: 10.1159/000542691. Epub ahead of print. PMID: 39586246.


Readhead B, Klang E, Gisladottir U, Vandromme M, Li L, Quiroz YT, Arboleda-Velasquez JF, Dudley JT, Tatonetti NP, Glicksberg BS, Reiman EM. Heparin treatment is associated with a delayed diagnosis of Alzheimer’s dementia in electronic health records from two large United States health systems. Mol Psychiatry. 2024 Oct 8. doi: 10.1038/s41380-024-02757-5. Epub ahead of print. PMID: 39379683.


Langella S, Bonta K, Chen Y, Su Y, Vasquez D, Aguillon D, Acosta-Baena N, Baena AY, Garcia-Ospina G, Giraldo-Chica M, Tirado V, Muñoz C, Ríos-Romenets S, Guzman-Martínez C, Pruzin JJ, Ghisays V, Arboleda-Velasquez JF, Kosik KS, Tariot PN, Reiman EM, Lopera F, Quiroz YT. Impact of APOE ε4 and ε2 on plasma neurofilament light chain and cognition in autosomal dominant Alzheimer’s disease. Alzheimers Res Ther. 2024 Oct 1;16(1):208. doi: 10.1186/s13195-024-01572-y. PMID: 39354618; PMCID: PMC11443799.


Ortiz-Acosta PK, Martínez JE, Vila-Castelar C, Fox-Fuller JT, Pluim C, Babulal GM, Ramírez-Gómez L, Munera D, Quiroz YT, Guzmán-Vélez E. Physical Activity and Neurocognitive Symptoms in Older Adults During COVID-19 Pandemic. J Appl Gerontol. 2025 Feb;44(2):327-336. doi: 10.1177/07334648241271975. Epub 2024 Sep 4. PMID: 39229852.


Acosta-Uribe J, Villegas-Lanau A, Vallejo D, Ramírez-Aguilar L, Solano JM, Mejía-Cupajita B, Aguillón D, Moreno S, Méndez LG, Baena A, Madrigal L, Bocanegra Y, Quiroz YT, García GP, Vasquez D, Arbeláez A, Lopera F, Beach TG, Kosik KS, White CL 3rd, Giraldo-Chica M. Primary lateral sclerosis associated with PSEN1 Pro284Leu variant in a Colombian family: Clinical and neuropathological features. Alzheimers Dement. 2024 Sep;20(9):6384-6394. doi: 10.1002/alz.14133. Epub 2024 Jul 27. PMID: 39072908; PMCID: PMC11497710.


Munro CE, Farrell M, Hanseeuw B, Rentz DM, Buckley R, Properzi M, Yuan Z, Vannini P, Amariglio RE, Quiroz YT, Blacker D, Sperling RA, Johnson KA, Marshall GA, Gatchel JR. Change in Depressive Symptoms and Longitudinal Regional Amyloid Accumulation in Unimpaired Older Adults. JAMA Netw Open. 2024 Aug 1;7(8):e2427248. doi: 10.1001/jamanetworkopen.2024.27248. PMID: 39207757; PMCID: PMC11362871.


Burling JE, Katz Z, Yuan Z, Munro C, Mimmack K, Ma G, Hanseeuw BJ, Papp KV, Amariglio RE, Vannini P, Rentz DM, Quiroz YT, Johnson KA, Sperling RA, Blacker D, Marshall GA, Yang HS, Gatchel JR. Study Partner Report of Apathy in Older Adults is Associated with AD Biomarkers: Findings from the Harvard Aging Brain Study. Am J Geriatr Psychiatry. 2024 Aug;32(8):909-919. doi: 10.1016/j.jagp.2024.01.020. Epub 2024 Jan 28. PMID: 38443298.


Quiroz YT, Aguillon D, Aguirre-Acevedo DC, Vasquez D, Zuluaga Y, Baena AY, Madrigal L, Hincapié L, Sanchez JS, Langella S, Posada-Duque R, Littau JL, Villalba-Moreno ND, Vila-Castelar C, Ramirez Gomez L, Garcia G, Kaplan E, Rassi Vargas S, Ossa JA, Valderrama-Carmona P, Perez-Corredor P, Krasemann S, Glatzel M, Kosik KS, Johnson K, Sperling RA, Reiman EM, Sepulveda-Falla D, Lopera F, Arboleda-Velasquez JF. APOE3 Christchurch Heterozygosity and Autosomal Dominant Alzheimer’s Disease. N Engl J Med. 2024 Jun 20;390(23):2156-2164. doi: 10.1056/NEJMoa2308583. PMID: 38899694.


Perez-Corredor P, Vanderleest TE, Vacano GN, Sanchez JS, Villalba-Moreno ND, Marino C, Krasemann S, Mendivil-Perez MA, Aguillón D, Jiménez-Del-Río M, Baena A, Sepulveda-Falla D, Lopera F, Quiroz YT, Arboleda-Velasquez JF, Mazzarino RC. APOE3 Christchurch modulates β-catenin/Wnt signaling in iPS cell-derived cerebral organoids from Alzheimer’s cases. Front Mol Neurosci. 2024 Mar 20; 17:1373568. doi: 10.3389/fnmol.2024.1373568. PMID: 38571814; PMCID: PMC10987717.


Keller G, Corvalan N, Carello MA, Arruabarrena MM, Martínez-Canyazo C, De Los Santos L, Spehrs J, Vila-Castelar C, Allegri RF, Quiroz YT, Crivelli L. Performance on the Latin American version of the Face-Name Associative Memory Exam (LAS-FNAME) distinguishes individuals with Mild Cognitive Impairment from age-matched controls in a sample from Argentina. Appl Neuropsychol Adult. 2024 Mar 6:1-9. doi: 10.1080/23279095.2024.2323627. Epub ahead of print. PMID: 38447166.


Sexton CE, Bitan G, Bowles KR, Brys M, Buée L, Maina MB, Clelland CD, Cohen AD, Crary JF, Dage JL, Diaz K, Frost B, Gan L, Goate AM, Golbe LI, Hansson O, Karch CM, Kolb HC, La Joie R, Lee SE, Matallana D, Miller BL, Onyike CU, Quiroz YT, Rexach JE, Rohrer JD, Rommel A, Sadri-Vakili G, Schindler SE, Schneider JA, Sperling RA, Teunissen CE, Weninger SC, Worley SL, Zheng H, Carrillo MC. Novel avenues of tau research. Alzheimers Dement. 2024 Mar;20(3):2240-2261. doi: 10.1002/alz.13533. Epub 2024 Jan 3. PMID: 38170841; PMCID: PMC10984447.


Langella S, Lopera F, Baena A, Fox-Fuller JT, Munera D, Martinez JE, Giudicessi A, Vannini P, Hanseeuw BJ, Marshall GA, Quiroz YT, Gatchel JR. Depressive symptoms and hippocampal volume in autosomal dominant Alzheimer’s disease. Alzheimers Dement. 2024 Feb;20(2):986-994. doi: 10.1002/alz.13501. Epub 2023 Oct 14. PMID: 37837524; PMCID: PMC10916972.


Giudicessi A, McDowell CP, Martinez JE, Baena A, Vila-Castelar C, Norton D, Aguirre-Acevedo DC, Tirado V, Bocanegra Y, Guzman-Velez E, Lopera F, Cronin-Golomb A, Quiroz YT. Cognitive Outcomes in Autosomal-Dominant Alzheimer’s Disease: A Comprehensive Review from a Colombian Kindred with the Presenilin-1 E280A Mutation. J Alzheimers Dis. 2024;101(2):397-415. doi: 10.3233/JAD-240360. PMID: 39213071; PMCID: PMC11616039.


Giudicessi A, Aduen PA, Fox-Fuller JT, Martinez JE, Gonzalez LA, Vila-Castelar C, Baena A, Pluim McDowell C, Cronin-Golomb A, Lopera F, Quiroz YT. The MAPP Room Memory Test: Examining Contextual Memory Using a Novel Computerized Test in Cognitively-Unimpaired Individuals with Autosomal Dominant Alzheimer’s Disease. J Prev Alzheimers Dis. 2024;11(2):463-468. doi: 10.14283/jpad.2024.7. PMID: 38374753.


Yucebas D, Fox-Fuller JT, Badillo Cabrera A, Baena A, Pluim McDowell C, Aduen P, Vila-Castelar C, Bocanegra Y, Tirado V, Sanchez JS, Cronin-Golomb A, Lopera F, Quiroz YT. Associations of category fluency clustering performance with in vivo brain pathology in autosomal dominant Alzheimer’s disease. J Int Neuropsychol Soc. 2024 Jan;30(1):77-83. doi: 10.1017/S1355617723000243. Epub 2023 Apr 26. PMID: 37185154; PMCID: PMC10600324.


Hanseeuw BJ, Jacobs HIL, Schultz AP, Buckley RF, Farrell ME, Guehl NJ, Becker JA, Properzi M, Sanchez JS, Quiroz YT, Vannini P, Sepulcre J, Yang HS, Chhatwal JP, Gatchel J, Marshall GA, Amariglio R, Papp K, Rentz DM, Normandin M, Price JC, Healy BC, El Fakhri G, Sperling RA, Johnson KA. Association of Pathologic and Volumetric Biomarker Changes With Cognitive Decline in Clinically Normal Adults. Neurology. 2023 Dec 12;101(24):e2533-e2544. doi: 10.1212/WNL.0000000000207962. Epub 2023 Nov 8. PMID: 37968130; PMCID: PMC10791053.


Nelson MR, Liu P, Agrawal A, Yip O, Blumenfeld J, Traglia M, Kim MJ, Koutsodendris N, Rao A, Grone B, Hao Y, Yoon SY, Xu Q, De Leon S, Choenyi T, Thomas R, Lopera F, Quiroz YT, Arboleda-Velasquez JF, Reiman EM, Mahley RW, Huang Y. The APOE-R136S mutation protects against APOE4-driven Tau pathology, neurodegeneration and neuroinflammation. Nat Neurosci. 2023 Dec;26(12):2104-2121. doi: 10.1038/s41593-023-01480-8. Epub 2023 Nov 13. PMID: 37957317; PMCID: PMC10689245.


Aguilar-Navarro SG, Sánchez BLP, Gutiérrez LAG, Arias-Trejo N, Quiroz YT, Alvarado AJM. Cross-cultural adaptation of the everyday cognition scale (M-ECog) in older Mexican adults with cognitive impairment. Dement Neuropsychol. 2023 Oct 23;17:e20230011. doi: 10.1590/1980-5764-DN-2023-0011. PMID: 37885966; PMCID: PMC10599302.


Vranceanu AM, Choukas NR, Rochon EA, Duarte B, Pietrzykowski MO, McDermott K, Hooker JE, Kulich R, Quiroz YT, Parker RA, Macklin EA, Ritchie C; Active Brains Project; Mace RA. Addressing the Chronic Pain-Early Cognitive Decline Comorbidity Among Older Adults: Protocol for the Active Brains Remote Efficacy Trial. JMIR Res Protoc. 2023 Sep 28;12:e47319. doi: 10.2196/47319. PMID: 37768713; PMCID: PMC10570897.


Vila-Castelar C, Chen Y, Langella S, Lopera F, Zetterberg H, Hansson O, Dage JL, Janelidzde S, Su Y, Chen K, Pluim McDowell C, Martinez JE, Ramirez-Gomez L, Garcia G, Aguillon D, Baena A, Giraldo-Chica M, Protas HD, Ghisays V, Rios-Romenets S, Tariot PN, Blennow K, Reiman EM, Quiroz YT. Sex differences in blood biomarkers and cognitive performance in individuals with autosomal dominant Alzheimer’s disease. Alzheimers Dement. 2023 Sep;19(9):4127-4138. doi: 10.1002/alz.13314. Epub 2023 Jun 6. PMID: 37279390; PMCID: PMC10527358.


Robinson T, Klinger H, Buckley R, Deters KD, Quiroz YT, Rentz D, Rabin JS, Sperling RA, Amariglio RE. Subjective cognitive decline across ethnoracial groups in the A4 study. Alzheimers Dement. 2023 Sep;19(9):4084-4093. doi: 10.1002/alz.13138. Epub 2023 May 23. PMID: 37218387; PMCID: PMC10524317.


Munro CE, Boyle R, Chen X, Coughlan G, Gonzalez C, Jutten RJ, Martinez J, Orlovsky I, Robinson T, Weizenbaum E, Pluim CF, Quiroz YT, Gatchel JR, Vannini P, Amariglio R. Recent contributions to the field of subjective cognitive decline in aging: A literature review. Alzheimers Dement (Amst). 2023 Oct 18;15(4):e12475. doi: 10.1002/dad2.12475. PMID: 37869044; PMCID: PMC10585124.


Langella S, Barksdale NG, Vasquez D, Aguillon D, Chen Y, Su Y, Acosta-Baena N, Acosta-Uribe J, Baena AY, Garcia-Ospina G, Giraldo-Chica M, Tirado V, Muñoz C, Ríos-Romenets S, Guzman-Martínez C, Oliveira G, Yang HS, Vila-Castelar C, Pruzin JJ, Ghisays V, Arboleda-Velasquez JF, Kosik KS, Reiman EM, Lopera F, Quiroz YT. Effect of apolipoprotein genotype and educational attainment on cognitive function in autosomal dominant Alzheimer’s disease. Nat Commun. 2023 Aug 23;14(1):5120. doi: 10.1038/s41467-023-40775-z.PMID: 37612284 


Vila-Castelar C, Chen Y, Langella S, Lopera F, Zetterberg H, Hansson O, Dage JL, Janelidzde S, Su Y, Chen K, Pluim McDowell C, Martinez JE, Ramirez-Gomez L, Garcia G, Aguillon D, Baena A, Giraldo-Chica M, Protas HD, Ghisays V, Rios-Romenets S, Tariot PN, Blennow K, Reiman EM, Quiroz YT. Sex differences in blood biomarkers and cognitive performance in individuals with autosomal dominant Alzheimer’s disease. Alzheimers Dement. 2023 Jun 6. doi: 10.1002/alz.13314. Epub ahead of print. PMID: 37279390.


Kloske CM, Barnum CJ, Batista AF, Bradshaw EM, Brickman AM, Bu G, Dennison J, Gearon MD, Goate AM, Haass C, Heneka MT, Hu WT, Huggins LKL, Jones NS, Koldamova R, Lemere CA, Liddelow SA, Marcora E, Marsh SE, Nielsen HM, Petersen KK, Petersen M, Piña-Escudero SD, Qiu WQ, Quiroz YT, Reiman E, Sexton C, Tansey MG, Tcw J, Teunissen CE, Tijms BM, van der Kant R, Wallings R, Weninger SC, Wharton W, Wilcock DM, Wishard TJ, Worley SL, Zetterberg H, Carrillo MC. APOE and immunity: Research highlights. Alzheimers Dement. 2023 Jun;19(6):2677-2696. doi: 10.1002/alz.13020. Epub 2023 Mar 28. PMID: 36975090.


Aguillon D, Langella S, Chen Y, Sanchez JS, Su Y, Vila-Castelar C, Vasquez D, Zetterberg H, Hansson O, Dage JL, Janelidze S, Chen K, Fox-Fuller JT, Aduen P, Martinez JE, Garcia G, Baena A, Guzman C, Johnson KA, Sperling RA, Blennow K, Reiman EM, Lopera F, Quiroz YT. Plasma p-tau217 predicts in vivo brain pathology and cognition in autosomal dominant Alzheimer’s disease. Alzheimers Dement. 2023 Jun;19(6):2585-2594. doi: 10.1002/alz.12906. Epub 2022 Dec 26. PMID: 36571821.


Robinson T, Klinger H, Buckley R, Deters KD, Quiroz YT, Rentz D, Rabin JS, Sperling RA, Amariglio RE. Subjective cognitive decline across ethnoracial groups in the A4 study. Alzheimers Dement. 2023 May 23. doi: 10.1002/alz.13138. Epub ahead of print. PMID: 37218387.


Lopera F, Marino C, Chandrahas AS, O’Hare M, Villalba-Moreno ND, Aguillon D, Baena A, Sanchez JS, Vila-Castelar C, Ramirez Gomez L, Chmielewska N, Oliveira GM, Littau JL, Hartmann K, Park K, Krasemann S, Glatzel M, Schoemaker D, Gonzalez-Buendia L, Delgado-Tirado S, Arevalo-Alquichire S, Saez-Torres KL, Amarnani D, Kim LA, Mazzarino RC, Gordon H, Bocanegra Y, Villegas A, Gai X, Bootwalla M, Ji J, Shen L, Kosik KS, Su Y, Chen Y, Schultz A, Sperling RA, Johnson K, Reiman EM, Sepulveda-Falla D, Arboleda-Velasquez JF, Quiroz YT. Resilience to autosomal dominant Alzheimer’s disease in a Reelin-COLBOS heterozygous man. Nat Med. 2023 May;29(5):1243-1252. doi: 10.1038/s41591-023-02318-3. Epub 2023 May 15. PMID: 37188781; PMCID: PMC10202812.


Reiman EM, Pruzin JJ, Rios-Romenets S, Brown C, Giraldo M, Acosta-Baena N, Tobon C, Hu N, Chen Y, Ghisays V, Enos J, Goradia DD, Lee W, Luo J, Malek-Ahmadi M, Protas H, Thomas RG, Chen K, Su Y, Boker C, Mastroeni D, Alvarez S, Quiroz YT, Langbaum JB, Sink KM, Lopera F, Tariot PN; and the API ADAD Colombia Trial Group. A public resource of baseline data from the Alzheimer’s Prevention Initiative Autosomal-Dominant Alzheimer’s Disease Trial. Alzheimers Dement. 2023 May;19(5):1938-1946. doi: 10.1002/alz.12843. Epub 2022 Nov 14. PMID: 36373344.


Yucebas D, Fox-Fuller JT, Badillo Cabrera A, Baena A, Pluim McDowell C, Aduen P, Vila-Castelar C, Bocanegra Y, Tirado V, Sanchez JS, Cronin-Golomb A, Lopera F, Quiroz YT. Associations of category fluency clustering performance with in vivo brain pathology in autosomal dominant Alzheimer’s disease. J Int Neuropsychol Soc. 2023 Apr 26:1-7. doi: 10.1017/S1355617723000243. Epub ahead of print. PMID: 37185154.


Pluim CF, Anzai JAU, Martinez JE, Munera D, Garza-Naveda AP, Vila-Castelar C, Guzmán-Vélez E, Ramirez-Gomez L, Bustin J, Serrano CM, Babulal GM, Okada de Oliveira M, Quiroz YT. Associations Among Loneliness, Purpose in Life and Subjective Cognitive Decline in Ethnoracially Diverse Older Adults Living in the United States. J Appl Gerontol. 2023 Mar;42(3):376-386. doi: 10.1177/07334648221139479. Epub 2022 Nov 17. PMID: 36396599; PMCID: PMC9679324.


Mazzarino RC, Perez-Corredor P, Vanderleest TE, Vacano GN, Sanchez JS, Villalba-Moreno ND, Krausemann S, Mendivil-Perez MA, Aguillón D, Jimenez-Del-Río M, Baena A, Sepulveda-Falla D, Lopera FJ, Quiroz YT, Arboleda-Velasquez JF. APOE3 Christchurch modulates tau phosphorylation and β-catenin/Wnt/Cadherin signaling in induced pluripotent stem cell-derived cerebral organoids from Alzheimer’s cases. bioRxiv [Preprint]. 2023 Jan 13:2023.01.11.523290. doi: 10.1101/2023.01.11.523290. PMID: 36712026; PMCID: PMC9882052.


Fox-Fuller JT, Martinez JE, Baena A, Londono N, Munera D, Noriega D, Vila-Castelar C, Aduen PA, Lopera F, Cronin-Golomb A, Quiroz YT. Memory for Semantically Related Objects Differentiates Cognitively Unimpaired Autosomal Dominant Mutation Carriers from Non-Carrier Family Members. J Prev Alzheimers Dis. 2023;10(2):322-327. doi: 10.14283/jpad.2023.14. PMID: 36946459; PMCID: PMC9871423.


Fortea J, Quiroz YT, Ryan NS. Lessons from Down syndrome and autosomal dominant Alzheimer’s disease. Lancet Neurol. 2023 Jan;22(1):5-6. doi: 10.1016/S1474-4422(22)00437-9. PMID: 36517171.


Mielke MM, Aggarwal NT, Vila-Castelar C, Agarwal P, Arenaza-Urquijo EM, Brett B, Brugulat-Serrat A, DuBose LE, Eikelboom WS, Flatt J, Foldi NS, Franzen S, Gilsanz P, Li W, McManus AJ, van Lent DM, Milani SA, Shaaban CE, Stites SD, Sundermann E, Suryadevara V, Trani JF, Turner AD, Vonk JMJ, Quiroz YT, Babulal GM; Diversity and Disparity Professional Interest Area Sex and Gender Special Interest Group. Consideration of sex and gender in Alzheimer’s disease and related disorders from a global perspective. Alzheimers Dement. 2022 Dec;18(12):2707-2724. doi: 10.1002/alz.12662. Epub 2022 Apr 8. PMID: 35394117; PMCID: PMC9547039.


Sepulveda-Falla D, Sanchez JS, Almeida MC, Boassa D, Acosta-Uribe J, Vila-Castelar C, Ramirez-Gomez L, Baena A, Aguillon D, Villalba-Moreno ND, Littau JL, Villegas A, Beach TG, White CL 3rd, Ellisman M, Krasemann S, Glatzel M, Johnson KA, Sperling RA, Reiman EM, Arboleda-Velasquez JF, Kosik KS, Lopera F, Quiroz YT. Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer’s dementia. Acta Neuropathol. 2022 Jul 15. doi: 10.1007/s00401-022-02467-8. Epub ahead of print. PMID: 35838824.


Schoemaker D, Zanon Zotin MC, Chen K, Igwe KC, Vila-Castelar C, Martinez J, Baena A, Fox-Fuller JT, Lopera F, Reiman EM, Brickman AM, Quiroz YT. White matter hyperintensities are a prominent feature of autosomal dominant Alzheimer’s disease that emerge prior to dementia. Alzheimers Res Ther. 2022 Jun 29; 14(1):89. PMID: 35768838.


Littau JL, Velilla L, Hase Y, Villalba-Moreno ND, Hagel C, Drexler D, Osorio Restrepo S, Villegas A, Lopera F, Vargas S, Glatzel M, Krasemann S, Quiroz YT, Arboleda-Velasquez JF, Kalaria R, Sepulveda-Falla D. Evidence of beta amyloid independent small vessel disease in familial Alzheimer’s disease. Brain Pathol. 2022 Jun 13; e13097. PMID: 35695802.


Gomez LR, Albers MW, Baena A, Vila-Castelar C, Fox-Fuller JT, Sanchez J, Jain F, Albers AD, Lopera F, Quiroz YT. Olfactory Function and Markers of Brain Pathology in Non-Demented Individuals with Autosomal Dominant Alzheimer’s Disease. J Alzheimers Dis. 2022 Jun 04. PMID: 35694921.


Mielke MM, Aggarwal NT, Vila-Castelar C, Agarwal P, Arenaza-Urquijo EM, Brett B, Brugulat-Serrat A, DuBose LE, Eikelboom WS, Flatt J, Foldi NS, Franzen S, Gilsanz P, Li W, McManus AJ, van Lent DM, Milani SA, Shaaban CE, Stites SD, Sundermann E, Suryadevara V, Trani JF, Turner AD, Vonk JMJ, Quiroz YT, Babulal GM. Consideration of sex and gender in Alzheimer’s disease and related disorders from a global perspective. Alzheimers Dement. 2022 Apr 08. PMID: 35394117.


Guzmán-Vélez E, Diez I, Schoemaker D, Pardilla-Delgado E, Vila-Castelar C, Fox-Fuller JT, Baena A, Sperling RA, Johnson KA, Lopera F, Sepulcre J, Quiroz YT. Amyloid-ß and tau pathologies relate to distinctive brain dysconnectomics in preclinical autosomal-dominant Alzheimer’s disease. Proc Natl Acad Sci U S A. 2022 04 12; 119(15):e2113641119. PMID: 35380901.


Prokopiou PC, Engels-Domínguez N, Papp KV, Scott MR, Schultz AP, Schneider C, Farrell ME, Buckley RF, Quiroz YT, El Fakhri G, Rentz DM, Sperling RA, Johnson KA, Jacobs HIL. Lower novelty-related locus coeruleus function is associated with Aß-related cognitive decline in clinically healthy individuals. Nat Commun. 2022 03 23; 13(1):1571. PMID: 35322012.


Jacobs HIL, Becker JA, Kwong K, Munera D, Ramirez-Gomez L, Engels-Domínguez N, Sanchez JS, Vila-Castelar C, Baena A, Sperling RA, Johnson KA, Lopera F, Quiroz YT. Waning locus coeruleus integrity precedes cortical tau accrual in preclinical autosomal dominant Alzheimer’s disease. Alzheimers Dement. 2022 Mar 17. PMID: 35298083.


Willey B, Mimmack K, Gagliardi G, Dossett ML, Wang S, Udeogu OJ, Donovan NJ, Gatchel JR, Quiroz YT, Amariglio R, Liu CH, Hyun S, ElTohamy A, Rentz D, Sperling RA, Marshall GA, Vannini P. Racial and socioeconomic status differences in stress, posttraumatic growth, and mental health in an older adult cohort during the COVID-19 pandemic. EClinicalMedicine. 2022 Mar; 45:101343. PMID: 35291556.


Vila-Castelar C, Fox-Fuller JT, Guzmán-Vélez E, Schoemaker D, Quiroz YT. A cultural approach to dementia – insights from US Latino and other minoritized groups. Nat Rev Neurol. 2022 05; 18(5):307-314. PMID: 35260817.


Levin J, Vöglein J, Quiroz YT, Bateman RJ, Ghisays V, Lopera F, McDade E, Reiman E, Tariot PN, Morris JC. Testing the amyloid cascade hypothesis: Prevention trials in autosomal dominant Alzheimer disease. Alzheimers Dement. 2022 Feb 24. PMID: 35212149.


Quiroz YT, Solis M, Aranda MP, Arbaje AI, Arroyo-Miranda M, Cabrera LY, Carrasquillo MM, Corrada MM, Crivelli L, Diminich ED, Dorsman KA, Gonzales M, González HM, Gonzalez-Seda AL, Grinberg LT, Guerrero LR, Hill CV, Jimenez-Velazquez IZ, Guerra JJL, Lopera F, Maestre G, Medina LD, O’Bryant S, Peñaloza C, Pinzon MM, Mavarez RVP, Pluim CF, Raman R, Rascovsky K, Rentz DM, Reyes Y, Rosselli M, Tansey MG, Vila-Castelar C, Zuelsdorff M, Carrillo M, Sexton C. Addressing the disparities in dementia risk, early detection and care in Latino populations: Highlights from the second Latinos & Alzheimer’s Symposium. Alzheimers Dement. 2022 Feb 24. PMID: 35199931.


Crivelli L, Quiroz YT, Calandri IL, Martin ME, Velilla LM, Cusicanqui MI, Yglesias FC, Llibre-Rodríguez JJ, Armele M, Román F, Barceló E, Dechent C, Carello MA, Olavarría L, Yassuda MS, Custodio N, Dansilio S, Sosa AL, Acosta DM, Brucki SMD, Caramelli P, Slachevsky A, Nitrini R, Carrillo MC, Allegri RF. Working Group Recommendations for the Practice of Teleneuropsychology in Latin America. Arch Clin Neuropsychol. 2022 Feb 22; 37(3):553-567. PMID: 34673890.


Vila-Castelar C, Tariot PN, Sink KM, Clayton D, Langbaum JB, Thomas RG, Chen Y, Su Y, Chen K, Hu N, Giraldo-Chica M, Tobón C, Acosta-Baena N, Luna E, Londoño M, Ospina P, Tirado V, Muñoz C, Henao E, Bocanegra Y, Alvarez S, Rios-Romenets S, Ghisays V, Goradia D, Lee W, Luo J, Malek-Ahmadi MH, Protas HD, Lopera F, Reiman EM, Quiroz YT. Sex differences in cognitive resilience in preclinical autosomal-dominant Alzheimer’s disease carriers and non-carriers: Baseline findings from the API ADAD Colombia Trial. Alzheimers Dement. 2022 Feb 01. PMID: 35103388.


Mace RA, Gates MV, Popok PJ, Kulich R, Quiroz YT, Vranceanu AM. Feasibility Trial of a Mind-Body Activity Pain Management Program for Older Adults With Cognitive Decline. Gerontologist. 2021 11 15; 61(8):1326-1337. PMID: 33159516.


Papp KV, Samaroo A, Chou HC, Buckley R, Schneider OR, Hsieh S, Soberanes D, Quiroz Y, Properzi M, Schultz A, García-Magariño I, Marshall GA, Burke JG, Kumar R, Snyder N, Johnson K, Rentz DM, Sperling RA, Amariglio RE. Unsupervised mobile cognitive testing for use in preclinical Alzheimer’s disease. Alzheimers Dement (Amst). 2021; 13(1):e12243. PMID: 34621977.


Sexton C, Snyder H, Beher D, Boxer AL, Brannelly P, Brion JP, Buée L, Cacace AM, Chételat G, Citron M, DeVos SL, Diaz K, Feldman HH, Frost B, Goate AM, Gold M, Hyman B, Johnson K, Karch CM, Kerwin DR, Koroshetz WJ, Litvan I, Morris HR, Mummery CJ, Mutamba J, Patterson MC, Quiroz YT, Rabinovici GD, Rommel A, Shulman MB, Toledo-Sherman LM, Weninger S, Wildsmith KR, Worley SL, Carrillo MC. Current directions in tau research: Highlights from Tau 2020. Alzheimers Dement. 2022 05; 18(5):988-1007. PMID: 34581500.


Fox-Fuller JT, Torrico-Teave H, d’Oleire Uquillas F, Chen K, Su Y, Chen Y, Brickhouse M, Sanchez JS, Aguero C, Jacobs HIL, Hampton O, Guzmán-Vélez E, Vila-Castelar C, Aguirre-Acevedo DC, Baena A, Artola A, Martinez J, Pluim CF, Alvarez S, Ochoa-Escudero M, Reiman EM, Sperling RA, Lopera F, Johnson KA, Dickerson BC, Quiroz YT. Cortical thickness across the lifespan in a Colombian cohort with autosomal-dominant Alzheimer’s disease: A cross-sectional study. Alzheimers Dement (Amst). 2021; 13(1):e12233. PMID: 34541287.


Vannini P, Gagliardi GP, Kuppe M, Dossett ML, Donovan NJ, Gatchel JR, Quiroz YT, Premnath PY, Amariglio R, Sperling RA, Marshall GA. Corrigendum to “Stress, resilience, and coping strategies in a sample of community-dwelling older adults during COVID-19” [J. Psychiatr. Res. 138 (2021) 176-185]. J Psychiatr Res. 2021 Oct; 142:167-170. PMID: 34359011.


Fox-Fuller JT, Artola A, Chen K, Pulsifer M, Ramirez D, Londono N, Aguirre-Acevedo DC, Vila-Castelar C, Baena A, Martinez J, Arboleda-Velasquez JF, Langbaum JB, Tariot PN, Reiman EM, Lopera F, Quiroz YT. Sex Differences in Cognitive Abilities Among Children With the Autosomal Dominant Alzheimer Disease Presenilin 1 E280A Variant From a Colombian Cohort. JAMA Netw Open. 2021 08 02; 4(8):e2121697. PMID: 34463747.


Fox-Fuller JT, Ngo J, Pluim CF, Kaplan RI, Kim DH, Anzai JAU, Yucebas D, Briggs SM, Aduen PA, Cronin-Golomb A, Quiroz YT. Initial investigation of test-retest reliability of home-to-home teleneuropsychological assessment in healthy, English-speaking adults. Clin Neuropsychol. 2021 Jul 26; 1-15. PMID: 34311660.


Velilla L, Hernández J, Giraldo-Chica M, Guzmán-Vélez E, Quiroz Y, Lopera F. A Spanish Neuropsychological Battery Discriminates Between the Behavioral Variant of Frontotemporal Dementia and Primary Progressive Aphasia in a Colombian Sample. Front Neurol. 2021; 12:656478. PMID: 34290661.


Ghisays V, Lopera F, Goradia DD, Protas HD, Malek-Ahmadi MH, Chen Y, Devadas V, Luo J, Lee W, Baena A, Bocanegra Y, Guzmán-Vélez E, Pardilla-Delgado E, Vila-Castelar C, Fox-Fuller JT, Hu N, Clayton D, Thomas RG, Alvarez S, Espinosa A, Acosta-Baena N, Giraldo MM, Rios-Romenets S, Langbaum JB, Chen K, Su Y, Tariot PN, Quiroz YT, Reiman EM. PET evidence of preclinical cerebellar amyloid plaque deposition in autosomal dominant Alzheimer’s disease-causing Presenilin-1 E280A mutation carriers. Neuroimage Clin. 2021; 31:102749. PMID: 34252876.


Raman R, Quiroz YT, Langford O, Choi J, Ritchie M, Baumgartner M, Rentz D, Aggarwal NT, Aisen P, Sperling R, Grill JD. Disparities by Race and Ethnicity Among Adults Recruited for a Preclinical Alzheimer Disease Trial. JAMA Netw Open. 2021 07 01; 4(7):e2114364. PMID: 34228129.


Martinez JE, Pardilla-Delgado E, Guzmán-Vélez E, Vila-Castelar C, Amariglio R, Gatchel J, Aguirre-Acevedo DC, Bocanegra Y, Baena A, Henao E, Tirado V, Muñoz C, Giraldo-Chica M, Lopera F, Quiroz YT. Subjective Cognitive Decline and its Relation to Verbal Memory and Sex in Cognitively Unimpaired Individuals from a Colombian Cohort with Autosomal-Dominant Alzheimer’s Disease. J Int Neuropsychol Soc. 2021 Jun 30; 1-9. PMID: 34187609.


Jacobs HIL, Schoemaker D, Torrico-Teave H, Zuluaga Y, Velilla-Jimenez L, Ospina-Villegas C, Lopera F, Arboleda-Velasquez JF, Quiroz YT. Specific Abnormalities in White Matter Pathways as Interface to Small Vessels Disease and Cognition in Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy Individuals. Brain Connect. 2022 02; 12(1):52-60. PMID: 33980027.


Pardilla-Delgado E, Torrico-Teave H, Sanchez JS, Ramirez-Gomez LA, Baena A, Bocanegra Y, Vila-Castelar C, Fox-Fuller JT, Guzmán-Vélez E, Martínez J, Alvarez S, Ochoa-Escudero M, Lopera F, Quiroz YT. Associations between subregional thalamic volume and brain pathology in autosomal dominant Alzheimer’s disease. Brain Commun. 2021; 3(2):fcab101. PMID: 34095834.


Babulal GM, Torres VL, Acosta D, Agüero C, Aguilar-Navarro S, Amariglio R, Ussui JA, Baena A, Bocanegra Y, Brucki SMD, Bustin J, Cabrera DM, Custodio N, Diaz MM, Peñailillo LD, Franco I, Gatchel JR, Garza-Naveda AP, González Lara M, Gutiérrez-Gutiérrez L, Guzmán-Vélez E, Hanseeuw BJ, Jimenez-Velazquez IZ, Rodríguez TL, Llibre-Guerra J, Marquine MJ, Martinez J, Medina LD, Miranda-Castillo C, Morlett Paredes A, Munera D, Nuñez-Herrera A, de Oliveira MO, Palmer-Cancel SJ, Pardilla-Delgado E, Perales-Puchalt J, Pluim C, Ramirez-Gomez L, Rentz DM, Rivera-Fernández C, Rosselli M, Serrano CM, Suing-Ortega MJ, Slachevsky A, Soto-Añari M, Sperling RA, Torrente F, Thumala D, Vannini P, Vila-Castelar C, Yañez-Escalante T, Quiroz YT. The impact of COVID-19 on the well-being and cognition of older adults living in the United States and Latin America. EClinicalMedicine. 2021 May; 35:100848. PMID: 33997742.


Mace RA, Gates MV, Bullard B, Lester EG, Silverman IH, Quiroz YT, Vranceanu AM. Development of a Novel Mind-Body Activity and Pain Management Program for Older Adults With Cognitive Decline. Gerontologist. 2021 04 03; 61(3):449-459. PMID: 32601670.


Vannini P, Gagliardi GP, Kuppe M, Dossett ML, Donovan NJ, Gatchel JR, Quiroz YT, Premnath PY, Amariglio R, Sperling RA, Marshall GA. Stress, resilience, and coping strategies in a sample of community-dwelling older adults during COVID-19. J Psychiatr Res. 2021 06; 138:176-185. PMID: 33862301.


Ibáñez A, Pina-Escudero SD, Possin KL, Quiroz YT, Peres FA, Slachevsky A, Sosa AL, Brucki SMD, Miller BL. Dementia caregiving across Latin America and the Caribbean and brain health diplomacy. Lancet Healthy Longev. 2021 Apr; 2(4):e222-e231. PMID: 34790905.


Guzmán-Vélez E, Zetterberg H, Fox-Fuller JT, Vila-Castelar C, Sanchez JS, Baena A, Garcia-Ospina G, Aguillon D, Pardilla-Delgado E, Gatchel JR, Sperling RA, Johnson K, Reiman EM, Blennow K, Lopera F, Quiroz YT. Associations between plasma neurofilament light, in vivo brain pathology, and cognition in non-demented individuals with autosomal-dominant Alzheimer’s disease. Alzheimers Dement. 2021 05; 17(5):813-821. PMID: 33527648.


Sanchez JS, Becker JA, Jacobs HIL, Hanseeuw BJ, Jiang S, Schultz AP, Properzi MJ, Katz SR, Beiser A, Satizabal CL, O’Donnell A, DeCarli C, Killiany R, El Fakhri G, Normandin MD, Gómez-Isla T, Quiroz YT, Rentz DM, Sperling RA, Seshadri S, Augustinack J, Price JC, Johnson KA. The cortical origin and initial spread of medial temporal tauopathy in Alzheimer’s disease assessed with positron emission tomography. Sci Transl Med. 2021 01 20; 13(577). PMID: 33472953.


Sanchez JS, Hanseeuw BJ, Lopera F, Sperling RA, Baena A, Bocanegra Y, Aguillon D, Guzmán-Vélez E, Pardilla-Delgado E, Ramirez-Gomez L, Vila-Castelar C, Martinez JE, Fox-Fuller JT, Ramos C, Ochoa-Escudero M, Alvarez S, Jacobs HIL, Schultz AP, Gatchel JR, Becker JA, Katz SR, Mayblyum DV, Price JC, Reiman EM, Johnson KA, Quiroz YT. Longitudinal amyloid and tau accumulation in autosomal dominant Alzheimer’s disease: findings from the Colombia-Boston (COLBOS) biomarker study. Alzheimers Res Ther. 2021 01 15; 13(1):27. PMID: 33451357.


Schoemaker D, Velilla-Jimenez L, Zuluaga Y, Baena A, Ospina C, Bocanegra Y, Alvarez S, Ochoa-Escudero M, Guzmán-Vélez E, Martinez J, Lopera F, Arboleda-Velasquez JF, Quiroz YT. Global Cardiovascular Risk Profile and Cerebrovascular Abnormalities in Presymptomatic Individuals with CADASIL or Autosomal Dominant Alzheimer’s Disease. J Alzheimers Dis. 2021; 82(2):841-853. PMID: 34092645.


Baena A, Bocanegra Y, Torres V, Vila-Castelar C, Guzmán-Vélez E, Fox-Fuller JT, Gatchel JR, Sánchez J, Pluim CF, Ramirez-Gómez L, Martínez J, Pineda D, Lopera F, Quiroz YT. Neuroticism Is Associated with Tau Pathology in Cognitively Unimpaired Individuals with Autosomal Dominant Alzheimer’s Disease. J Alzheimers Dis. 2021; 82(4):1809-1822. PMID: 34219716.


Armstrong GW, Kim LA, Vingopoulos F, Park JY, Garg I, Kasetty M, Silverman RF, Zeng R, Douglas VP, Lopera F, Baena A, Giraldo M, Norton D, Cronin-Golomb A, Arboleda-Velasquez JF, Quiroz YT, Miller JB. Retinal Imaging Findings in Carriers With PSEN1-Associated Early-Onset Familial Alzheimer Disease Before Onset of Cognitive Symptoms. JAMA Ophthalmol. 2021 01 01; 139(1):49-56. PMID: 33180114.


Vannini P, Hanseeuw BJ, Gatchel JR, Sikkes SAM, Alzate D, Zuluaga Y, Moreno S, Mendez L, Baena A, Ospina-Lopera P, Tirado V, Henao E, Acosta-Baena N, Giraldo M, Lopera F, Quiroz YT. Trajectory of Unawareness of Memory Decline in Individuals With Autosomal Dominant Alzheimer Disease. JAMA Netw Open. 2020 12 01; 3(12):e2027472. PMID: 33263761.


Parra MA, Baez S, Sedeño L, Gonzalez Campo C, Santamaría-García H, Aprahamian I, Bertolucci PH, Bustin J, Camargos Bicalho MA, Cano-Gutierrez C, Caramelli P, Chaves MLF, Cogram P, Beber BC, Court FA, de Souza LC, Custodio N, Damian A, de la Cruz M, Diehl Rodriguez R, Brucki SMD, Fajersztajn L, Farías GA, De Felice FG, Ferrari R, de Oliveira FF, Ferreira ST, Ferretti C, Figueredo Balthazar ML, Ferreira Frota NA, Fuentes P, García AM, Garcia PJ, de Gobbi Porto FH, Duque Peñailillo L, Engler HW, Maier I, Mata IF, Gonzalez-Billault C, Lopez OL, Morelli L, Nitrini R, Quiroz YT, Guerrero Barragan A, Huepe D, Pio FJ, Suemoto CK, Kochhann R, Kochen S, Kumfor F, Lanata S, Miller B, Mansur LL, Hosogi ML, Lillo P, Llibre Guerra J, Lira D, Lopera F, Comas A, Avila-Funes JA, Sosa AL, Ramos C, Resende EPF, Snyder HM, Tarnanas I, Yokoyama J, Llibre J, Cardona JF, Possin K, Kosik KS, Montesinos R, Moguilner S, Solis PCL, Ferretti-Rebustini REL, Ramirez JM, Matallana D, Mbakile-Mahlanza L, Marques Ton AM, Tavares RM, Miotto EC, Muniz-Terrera G, Muñoz-Nevárez LA, Orozco D, Okada de Oliveira M, Piguet O, Pintado Caipa M, Piña Escudero SD, Schilling LP, Rodrigues Palmeira AL, Yassuda MS, Santacruz-Escudero JM, Serafim RB, Smid J, Slachevsky A, Serrano C, Soto-Añari M, Takada LT, Grinberg LT, Teixeira AL, Barbosa MT, Trépel D, Ibanez A. Dementia in Latin America: Paving the way toward a regional action plan. Alzheimers Dement. 2021 02; 17(2):295-313. PMID: 33634602.


García-Magariño I, Fox-Fuller JT, Palacios-Navarro G, Baena A, Quiroz YT. Visual working memory for semantically related objects in healthy adults. Rev Neurol. 2020 Oct 16; 71(8):277-284. PMID: 33034365.


Ospina C, Arboleda-Velasquez JF, Aguirre-Acevedo DC, Zuluaga-Castaño Y, Velilla L, Garcia GP, Quiroz YT, Lopera F. Genetic and nongenetic factors associated with CADASIL: A retrospective cohort study. J Neurol Sci. 2020 Dec 15; 419:117178. PMID: 33091750.


Schoemaker D, Zuluaga Y, Viswanathan A, Schirmer MD, Torrico-Teave H, Velilla L, Ospina C, Ospina GG, Lopera F, Arboleda-Velasquez JF, Quiroz YT. The INECO Frontal Screening for the Evaluation of Executive Dysfunction in Cerebral Small Vessel Disease: Evidence from Quantitative MRI in a CADASIL Cohort from Colombia – Corrigendum. J Int Neuropsychol Soc. 2020 11; 26(10):1052. PMID: 32967748.


Vila-Castelar C, Muñoz N, Papp KV, Amariglio RE, Baena A, Guzmán-Vélez E, Bocanegra Y, Sanchez JS, Reiman EM, Johnson KA, Sperling RA, Lopera F, Rentz DM, Quiroz YT. The Latin American Spanish version of the Face-Name Associative Memory Exam is sensitive to cognitive and pathological changes in preclinical autosomal dominant Alzheimer’s disease. Alzheimers Res Ther. 2020 09 10; 12(1):104. PMID: 32912283.


Palmqvist S, Janelidze S, Quiroz YT, Zetterberg H, Lopera F, Stomrud E, Su Y, Chen Y, Serrano GE, Leuzy A, Mattsson-Carlgren N, Strandberg O, Smith R, Villegas A, Sepulveda-Falla D, Chai X, Proctor NK, Beach TG, Blennow K, Dage JL, Reiman EM, Hansson O. Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders. JAMA. 2020 08 25; 324(8):772-781. PMID: 32722745.


Norton DJ, Parra MA, Sperling RA, Baena A, Guzman-Velez E, Jin DS, Andrea N, Khang J, Schultz A, Rentz DM, Pardilla-Delgado E, Fuller J, Johnson K, Reiman EM, Lopera F, Quiroz YT. Visual short-term memory relates to tau and amyloid burdens in preclinical autosomal dominant Alzheimer’s disease. Alzheimers Res Ther. 2020 08 21; 12(1):99. PMID: 32825838.


Bocanegra Y, Fox-Fuller JT, Baena A, Guzmán-Vélez E, Vila-Castelar C, Martínez J, Torrico-Teave H, Lopera F, Quiroz YT. Association Between Visual Memory and In Vivo Amyloid and Tau Pathology in Preclinical Autosomal Dominant Alzheimer’s Disease. J Int Neuropsychol Soc. 2021 01; 27(1):47-55. PMID: 32762790.


Kivipelto M, Mangialasche F, Snyder HM, Allegri R, Andrieu S, Arai H, Baker L, Belleville S, Brodaty H, Brucki SM, Calandri I, Caramelli P, Chen C, Chertkow H, Chew E, Choi SH, Chowdhary N, Crivelli L, Torre R, Du Y, Dua T, Espeland M, Feldman HH, Hartmanis M, Hartmann T, Heffernan M, Henry CJ, Hong CH, Håkansson K, Iwatsubo T, Jeong JH, Jimenez-Maggiora G, Koo EH, Launer LJ, Lehtisalo J, Lopera F, Martínez-Lage P, Martins R, Middleton L, Molinuevo JL, Montero-Odasso M, Moon SY, Morales-Pérez K, Nitrini R, Nygaard HB, Park YK, Peltonen M, Qiu C, Quiroz YT, Raman R, Rao N, Ravindranath V, Rosenberg A, Sakurai T, Salinas RM, Scheltens P, Sevlever G, Soininen H, Sosa AL, Suemoto CK, Tainta-Cuezva M, Velilla L, Wang Y, Whitmer R, Xu X, Bain LJ, Solomon A, Ngandu T, Carrillo MC. World-Wide FINGERS Network: A global approach to risk reduction and prevention of dementia. Alzheimers Dement. 2020 07; 16(7):1078-1094. PMID: 32627328.


Guzmán-Vélez E, Martínez J, Papp K, Baena A, Vila-Castelar C, Artola A, Schultz AP, Bocanegra Y, Sanchez J, Rentz D, Tariot PN, Reiman EM, Sperling R, Johnson KA, Lopera F, Quiroz YT. Associative memory and in vivo brain pathology in asymptomatic presenilin-1 E280A carriers. Neurology. 2020 09 08; 95(10):e1312-e1321. PMID: 32611637.


Schoemaker D, Zuluaga Y, Viswanathan A, Shrimer D, Torrico-Teave H, Velilla L, Ospina C, Ospina GG, Lopera F, Arboleda-Velasquez JF, Quiroz YT. The INECO Frontal Screening for the Evaluation of Executive Dysfunction in Cerebral Small Vessel Disease: Evidence from Quantitative MRI in a CADASIL Cohort from Colombia. J Int Neuropsychol Soc. 2020 11; 26(10):1006-1018. PMID: 32487276.


Quiroz YT, Zetterberg H, Reiman EM, Chen Y, Su Y, Fox-Fuller JT, Garcia G, Villegas A, Sepulveda-Falla D, Villada M, Arboleda-Velasquez JF, Guzmán-Vélez E, Vila-Castelar C, Gordon BA, Schultz SA, Protas HD, Ghisays V, Giraldo M, Tirado V, Baena A, Munoz C, Rios-Romenets S, Tariot PN, Blennow K, Lopera F. Plasma neurofilament light chain in the presenilin 1 E280A autosomal dominant Alzheimer’s disease kindred: a cross-sectional and longitudinal cohort study. Lancet Neurol. 2020 06; 19(6):513-521. PMID: 32470423.


Rios-Romenets S, Lopera F, Sink KM, Hu N, Lian Q, Guthrie H, Smith J, Cho W, Mackey H, Langbaum JB, Thomas RG, Giraldo-Chica M, Tobon C, Acosta-Baena N, Muñoz C, Ospina P, Tirado V, Henao E, Bocanegra Y, Chen K, Su Y, Goradia D, Thiyyagura P, VanGilder PS, Luo J, Ghisays V, Lee W, Malek-Ahmadi MH, Protas HD, Chen Y, Quiroz YT, Reiman EM, Tariot PN. Baseline demographic, clinical, and cognitive characteristics of the Alzheimer’s Prevention Initiative (API) Autosomal-Dominant Alzheimer’s Disease Colombia Trial. Alzheimers Dement. 2020 07; 16(7):1023-1030. PMID: 32418361.


Reiman EM, Arboleda-Velasquez JF, Quiroz YT, Huentelman MJ, Beach TG, Caselli RJ, Chen Y, Su Y, Myers AJ, Hardy J, Paul Vonsattel J, Younkin SG, Bennett DA, De Jager PL, Larson EB, Crane PK, Keene CD, Kamboh MI, Kofler JK, Duque L, Gilbert JR, Gwirtsman HE, Buxbaum JD, Dickson DW, Frosch MP, Ghetti BF, Lunetta KL, Wang LS, Hyman BT, Kukull WA, Foroud T, Haines JL, Mayeux RP, Pericak-Vance MA, Schneider JA, Trojanowski JQ, Farrer LA, Schellenberg GD, Beecham GW, Montine TJ, Jun GR. Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study. Nat Commun. 2020 02 03; 11(1):667. PMID: 32015339.


Amariglio RE, Buckley RF, Rabin JS, Papp KV, Quiroz YT, Mormino EC, Sparks KP, Johnson KA, Rentz DM, Sperling RA. Examining Cognitive Decline Across Black and White Participants in the Harvard Aging Brain Study. J Alzheimers Dis. 2020; 75(4):1437-1446. PMID: 32417775.


Vila-Castelar C, Guzmán-Vélez E, Pardilla-Delgado E, Buckley RF, Bocanegra Y, Baena A, Fox-Fuller JT, Tirado V, Muñoz C, Giraldo M, Acosta-Baena N, Rios-Romenets S, Langbaum JB, Tariot PN, Lopera F, Reiman EM, Quiroz YT. Examining Sex Differences in Markers of Cognition and Neurodegeneration in Autosomal Dominant Alzheimer’s Disease: Preliminary Findings from the Colombian Alzheimer’s Prevention Initiative Biomarker Study. J Alzheimers Dis. 2020; 77(4):1743-1753. PMID: 32925067.


Gatchel JR, Lopera F, Norton DJ, Baena A, Guzman-Velez E, Sanchez JS, d’Oleire Uquillas F, Schultz A, Vannini P, Artola A, Amariglio RE, Rentz DM, Tariot PN, Reiman EM, Johnson KA, Sperling RA, Marshall GA, Quiroz YT. Association of subjective cognitive decline with markers of brain pathology in preclinical autosomal dominant Alzheimer’s disease. J Neurol Neurosurg Psychiatry. 2020 03; 91(3):330-332. PMID: 31874859.


Vila-Castelar C, Papp KV, Amariglio RE, Torres VL, Baena A, Gomez D, Rendon J, Samaroo A, Lopera F, Rentz DM, Quiroz YT. Validation of the Latin American Spanish version of the face-name associative memory exam in a Colombian Sample. Clin Neuropsychol. 2020 12; 34(sup1):1-12. PMID: 31851865.


Arboleda-Velasquez JF, Lopera F, O’Hare M, Delgado-Tirado S, Marino C, Chmielewska N, Saez-Torres KL, Amarnani D, Schultz AP, Sperling RA, Leyton-Cifuentes D, Chen K, Baena A, Aguillon D, Rios-Romenets S, Giraldo M, Guzmán-Vélez E, Norton DJ, Pardilla-Delgado E, Artola A, Sanchez JS, Acosta-Uribe J, Lalli M, Kosik KS, Huentelman MJ, Zetterberg H, Blennow K, Reiman RA, Luo J, Chen Y, Thiyyagura P, Su Y, Jun GR, Naymik M, Gai X, Bootwalla M, Ji J, Shen L, Miller JB, Kim LA, Tariot PN, Johnson KA, Reiman EM, Quiroz YT. Resistance to autosomal dominant Alzheimer’s disease in an APOE3 Christchurch homozygote: a case report. Nat Med. 2019 11; 25(11):1680-1683. PMID: 31686034.


Rabin JS, Klein H, Kirn DR, Schultz AP, Yang HS, Hampton O, Jiang S, Buckley RF, Viswanathan A, Hedden T, Pruzin J, Yau WW, Guzmán-Vélez E, Quiroz YT, Properzi M, Marshall GA, Rentz DM, Johnson KA, Sperling RA, Chhatwal JP. Associations of Physical Activity and ß-Amyloid With Longitudinal Cognition and Neurodegeneration in Clinically Normal Older Adults. JAMA Neurol. 2019 Oct 01; 76(10):1203-1210. PMID: 31312836.


Gatchel JR, Rabin JS, Buckley RF, Locascio JJ, Quiroz YT, Yang HS, Vannini P, Amariglio RE, Rentz DM, Properzi M, Donovan NJ, Blacker D, Johnson KA, Sperling RA, Marshall GA. Longitudinal Association of Depression Symptoms With Cognition and Cortical Amyloid Among Community-Dwelling Older Adults. JAMA Netw Open. 2019 08 02; 2(8):e198964. PMID: 31397865.


Hanseeuw BJ, Betensky RA, Jacobs HIL, Schultz AP, Sepulcre J, Becker JA, Cosio DMO, Farrell M, Quiroz YT, Mormino EC, Buckley RF, Papp KV, Amariglio RA, Dewachter I, Ivanoiu A, Huijbers W, Hedden T, Marshall GA, Chhatwal JP, Rentz DM, Sperling RA, Johnson K. Association of Amyloid and Tau With Cognition in Preclinical Alzheimer Disease: A Longitudinal Study. JAMA Neurol. 2019 Aug 01; 76(8):915-924. PMID: 31157827.


Torres VL, Vila-Castelar C, Bocanegra Y, Baena A, Guzmán-Vélez E, Aguirre-Acevedo DC, Tirado V, Munoz C, Henao E, Moreno S, Giraldo M, Acosta N, Rios Romenets S, Langbaum JB, Cho W, Reiman EM, Tariot PN, Rosselli M, Quiroz YT, Lopera F. Normative data stratified by age and education for a Spanish neuropsychological test battery: Results from the Colombian Alzheimer’s prevention initiative registry. Appl Neuropsychol Adult. 2021 Mar-Apr; 28(2):230-244. PMID: 31230490.


Ramirez Aguilar L, Acosta-Uribe J, Giraldo MM, Moreno S, Baena A, Alzate D, Cuastumal R, Aguillón D, Madrigal L, Saldarriaga A, Navarro A, Garcia GP, Aguirre-Acevedo DC, Geier EG, Cochran JN, Quiroz YT, Myers RM, Yokoyama JS, Kosik KS, Lopera F. Genetic origin of a large family with a novel PSEN1 mutation (Ile416Thr). Alzheimers Dement. 2019 05; 15(5):709-719. PMID: 30745123.


Hanseeuw BJ, Lopera F, Sperling RA, Norton DJ, Guzman-Velez E, Baena A, Pardilla-Delgado E, Schultz AP, Gatchel J, Jin D, Chen K, Reiman EM, Johnson KA, Quiroz YT. Striatal amyloid is associated with tauopathy and memory decline in familial Alzheimer’s disease. Alzheimers Res Ther. 2019 02 04; 11(1):17. PMID: 30717814.


Sperling RA, Mormino EC, Schultz AP, Betensky RA, Papp KV, Amariglio RE, Hanseeuw BJ, Buckley R, Chhatwal J, Hedden T, Marshall GA, Quiroz YT, Donovan NJ, Jackson J, Gatchel JR, Rabin JS, Jacobs H, Yang HS, Properzi M, Kirn DR, Rentz DM, Johnson KA. The impact of amyloid-beta and tau on prospective cognitive decline in older individuals. Ann Neurol. 2019 02; 85(2):181-193. PMID: 30549303.


Schoemaker D, Quiroz YT, Torrico-Teave H, Arboleda-Velasquez JF. Clinical and research applications of magnetic resonance imaging in the study of CADASIL. Neurosci Lett. 2019 04 17; 698:173-179. PMID: 30634011.


Fuller JT, Cronin-Golomb A, Gatchel JR, Norton DJ, Guzmán-Vélez E, Jacobs HIL, Hanseeuw B, Pardilla-Delgado E, Artola A, Baena A, Bocanegra Y, Kosik KS, Chen K, Tariot PN, Johnson K, Sperling RA, Reiman EM, Lopera F, Quiroz YT. Biological and Cognitive Markers of Presenilin1 E280A Autosomal Dominant Alzheimer’s Disease: A Comprehensive Review of the Colombian Kindred. J Prev Alzheimers Dis. 2019; 6(2):112-120. PMID: 30756118.


Babulal GM, Quiroz YT, Albensi BC, Arenaza-Urquijo E, Astell AJ, Babiloni C, Bahar-Fuchs A, Bell J, Bowman GL, Brickman AM, Chételat G, Ciro C, Cohen AD, Dilworth-Anderson P, Dodge HH, Dreux S, Edland S, Esbensen A, Evered L, Ewers M, Fargo KN, Fortea J, Gonzalez H, Gustafson DR, Head E, Hendrix JA, Hofer SM, Johnson LA, Jutten R, Kilborn K, Lanctôt KL, Manly JJ, Martins RN, Mielke MM, Morris MC, Murray ME, Oh ES, Parra MA, Rissman RA, Roe CM, Santos OA, Scarmeas N, Schneider LS, Schupf N, Sikkes S, Snyder HM, Sohrabi HR, Stern Y, Strydom A, Tang Y, Terrera GM, Teunissen C, Melo van Lent D, Weinborn M, Wesselman L, Wilcock DM, Zetterberg H, O’Bryant SE. Perspectives on ethnic and racial disparities in Alzheimer’s disease and related dementias: Update and areas of immediate need. Alzheimers Dement. 2019 02; 15(2):292-312. PMID: 30555031.


Rendon J, Zuluaga Y, Velilla L, Ochoa J, Arboleda-Velasquez JF, Budson A, Lopera F, Quiroz YT. Event-related potential correlates of recognition memory in asymptomatic individuals with CADASIL. Brain Res. 2019 03 15; 1707:74-78. PMID: 30445028.


Zuluaga-Castaño Y, Montoya-Arenas DA, Velilla L, Ospina C, Arboleda-Velasquez JF, Quiroz YT, Lopera F. Cognitive performance in asymptomatic carriers of mutations R1031C and R141C in CADASIL. Int J Psychol Res (Medellin). 2018 Jul-Dec; 11(2):46-55. PMID: 32612778.


Quiroz YT, Sperling RA, Norton DJ, Baena A, Arboleda-Velasquez JF, Cosio D, Schultz A, Lapoint M, Guzman-Velez E, Miller JB, Kim LA, Chen K, Tariot PN, Lopera F, Reiman EM, Johnson KA. Association Between Amyloid and Tau Accumulation in Young Adults With Autosomal Dominant Alzheimer Disease. JAMA Neurol. 2018 05 01; 75(5):548-556. PMID: 29435558.


Guzmán-Vélez E, Jaimes S, Aguirre-Acevedo DC, Norton DJ, Papp KV, Amariglio R, Rentz D, Baena A, Henao E, Tirado V, Muñoz C, Giraldo M, Sperling RA, Lopera F, Quiroz YT. A Three-Factor Structure of Cognitive Functioning Among Unimpaired Carriers and Non-Carriers of Autosomal-Dominant Alzheimer’s Disease. J Alzheimers Dis. 2018; 65(1):107-115. PMID: 30040714.


Penny W, Iglesias-Fuster J, Quiroz YT, Lopera FJ, Bobes MA. Dynamic Causal Modeling of Preclinical Autosomal-Dominant Alzheimer’s Disease. J Alzheimers Dis. 2018; 65(3):697-711. PMID: 29562504.


Norton DJ, Amariglio R, Protas H, Chen K, Aguirre-Acevedo DC, Pulsifer B, Castrillon G, Tirado V, Munoz C, Tariot P, Langbaum JB, Reiman EM, Lopera F, Sperling RA, Quiroz YT. Subjective memory complaints in preclinical autosomal dominant Alzheimer disease. Neurology. 2017 Oct 03; 89(14):1464-1470. PMID: 28878053.


Papp KV, Rentz DM, Mormino EC, Schultz AP, Amariglio RE, Quiroz Y, Johnson KA, Sperling RA. Cued memory decline in biomarker-defined preclinical Alzheimer disease. Neurology. 2017 Apr 11; 88(15):1431-1438. PMID: 28283594.


Mormino EC, Papp KV, Rentz DM, Donohue MC, Amariglio R, Quiroz YT, Chhatwal J, Marshall GA, Donovan N, Jackson J, Gatchel JR, Hanseeuw BJ, Schultz AP, Aisen PS, Johnson KA, Sperling RA. Early and late change on the preclinical Alzheimer’s cognitive composite in clinically normal older individuals with elevated amyloid ß. Alzheimers Dement. 2017 Sep; 13(9):1004-1012. PMID: 28253478.


Primo V, Graham M, Bigger-Allen AA, Chick JM, Ospina C, Quiroz YT, Manent J, Gygi SP, Lopera F, D’Amore PA, Arboleda-Velasquez JF. Blood biomarkers in a mouse model of CADASIL. Brain Res. 2016 08 01; 1644:118-26. PMID: 27174004.


Aguirre-Acevedo DC, Lopera F, Henao E, Tirado V, Muñoz C, Giraldo M, Bangdiwala SI, Reiman EM, Tariot PN, Langbaum JB, Quiroz YT, Jaimes F. Cognitive Decline in a Colombian Kindred With Autosomal Dominant Alzheimer Disease: A Retrospective Cohort Study. JAMA Neurol. 2016 Apr; 73(4):431-8. PMID: 26902171.


Quiroz YT, Schultz AP, Chen K, Protas HD, Brickhouse M, Fleisher AS, Langbaum JB, Thiyyagura P, Fagan AM, Shah AR, Muniz M, Arboleda-Velasquez JF, Munoz C, Garcia G, Acosta-Baena N, Giraldo M, Tirado V, Ramírez DL, Tariot PN, Dickerson BC, Sperling RA, Lopera F, Reiman EM. Brain Imaging and Blood Biomarker Abnormalities in Children With Autosomal Dominant Alzheimer Disease: A Cross-Sectional Study. JAMA Neurol. 2015 Aug; 72(8):912-9. PMID: 26121081.


Fleisher AS, Chen K, Quiroz YT, Jakimovich LJ, Gutierrez Gomez M, Langois CM, Langbaum JB, Roontiva A, Thiyyagura P, Lee W, Ayutyanont N, Lopez L, Moreno S, Muñoz C, Tirado V, Acosta-Baena N, Fagan AM, Giraldo M, Garcia G, Huentelman MJ, Tariot PN, Lopera F, Reiman EM. Associations between biomarkers and age in the presenilin 1 E280A autosomal dominant Alzheimer disease kindred: a cross-sectional study. JAMA Neurol. 2015 Mar; 72(3):316-24. PMID: 25580592.


Quiroz YT, Willment KC, Castrillon G, Muniz M, Lopera F, Budson A, Stern CE. Successful Scene Encoding in Presymptomatic Early-Onset Alzheimer’s Disease. J Alzheimers Dis. 2015; 47(4):955-64. PMID: 26401774.


Rodriguez R, Lopera F, Alvarez A, Fernandez Y, Galan L, Quiroz Y, Bobes MA. Spectral Analysis of EEG in Familial Alzheimer’s Disease with E280A Presenilin-1 Mutation Gene. Int J Alzheimers Dis. 2014; 2014:180741. PMID: 24551475.


Langbaum JB, Fleisher AS, Chen K, Ayutyanont N, Lopera F, Quiroz YT, Caselli RJ, Tariot PN, Reiman EM. Ushering in the study and treatment of preclinical Alzheimer disease. Nat Rev Neurol. 2013 Jul; 9(7):371-81. PMID: 23752908.


Quiroz YT, Stern CE, Reiman EM, Brickhouse M, Ruiz A, Sperling RA, Lopera F, Dickerson BC. Cortical atrophy in presymptomatic Alzheimer’s disease presenilin 1 mutation carriers. J Neurol Neurosurg Psychiatry. 2013 May; 84(5):556-61. PMID: 23134660.


Fleisher AS, Chen K, Quiroz YT, Jakimovich LJ, Gomez MG, Langois CM, Langbaum JB, Ayutyanont N, Roontiva A, Thiyyagura P, Lee W, Mo H, Lopez L, Moreno S, Acosta-Baena N, Giraldo M, Garcia G, Reiman RA, Huentelman MJ, Kosik KS, Tariot PN, Lopera F, Reiman EM. Florbetapir PET analysis of amyloid-ß deposition in the presenilin 1 E280A autosomal dominant Alzheimer’s disease kindred: a cross-sectional study. Lancet Neurol. 2012 Dec; 11(12):1057-65. PMID: 23137949.


Reiman EM, Quiroz YT, Fleisher AS, Chen K, Velez-Pardo C, Jimenez-Del-Rio M, Fagan AM, Shah AR, Alvarez S, Arbelaez A, Giraldo M, Acosta-Baena N, Sperling RA, Dickerson B, Stern CE, Tirado V, Munoz C, Reiman RA, Huentelman MJ, Alexander GE, Langbaum JB, Kosik KS, Tariot PN, Lopera F. Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer’s disease in the presenilin 1 E280A kindred: a case-control study. Lancet Neurol. 2012 Dec; 11(12):1048-56. PMID: 23137948.


Quiroz YT, Lopera F, Budson AE. Charting the path for early diagnosis and prevention of Alzheimer’s disease. Expert Rev Neurother. 2011 Dec; 11(12):1665-7. PMID: 22091590.


Quiroz YT, Ally BA, Celone K, McKeever J, Ruiz-Rizzo AL, Lopera F, Stern CE, Budson AE. Event-related potential markers of brain changes in preclinical familial Alzheimer disease. Neurology. 2011 Aug 02; 77(5):469-75. PMID: 21775732.


Reiman EM, Langbaum JB, Fleisher AS, Caselli RJ, Chen K, Ayutyanont N, Quiroz YT, Kosik KS, Lopera F, Tariot PN. Alzheimer’s Prevention Initiative: a plan to accelerate the evaluation of presymptomatic treatments. J Alzheimers Dis. 2011; 26 Suppl 3:321-9. PMID: 21971471.


Quiroz YT, Budson AE, Celone K, Ruiz A, Newmark R, Castrillón G, Lopera F, Stern CE. Hippocampal hyperactivation in presymptomatic familial Alzheimer’s disease. Ann Neurol. 2010 Dec; 68(6):865-75. PMID: 21194156.


Bobes MA, García YF, Lopera F, Quiroz YT, Galán L, Vega M, Trujillo N, Valdes-Sosa M, Valdes-Sosa P. ERP generator anomalies in presymptomatic carriers of the Alzheimer’s disease E280A PS-1 mutation. Hum Brain Mapp. 2010 Feb; 31(2):247-65. PMID: 19650138.


Schon K, Quiroz YT, Hasselmo ME, Stern CE. Greater working memory load results in greater medial temporal activity at retrieval. Cereb Cortex. 2009 Nov; 19(11):2561-71. PMID: 19224975.